生理學系，副教授
職稱：副教授
學科專業：生理學
研究方向：神經精神疾病發病機制研究
電子郵箱：jiczhang825@qq.com
個人簡介：醫學博士，太阳集团app首页基礎醫學院生理系副教授。2013年畢業于日本千葉大學（Chiba University），獲醫學博士學位。分别曾在日本千葉大學，美國Emory大學，東京醫科齒科大學從事博士後及助理教授研究工作。主要研究領域：抑郁症，阿爾茨海默病及帕金森病的發病機制研究。近年來在Biology Psychiatry、PNAS、Mol Psychiatry、Transl Psychiatry 等著名國際主流學術期刊發表SCI論文50餘篇。
2019.07-至今，太阳集团app首页基礎醫學院生理學系，副教授
2017.11-2019.06，東京醫科齒科大學神經病态學系，助理教授（日本）
2016.11-2017.09，埃默裡大學病理和實驗醫學系，博士後（美國）
2013.10-2016.10，千葉大學社會精神保健教育研究中心，助理教授（日本）
2010.04-2013.09，千葉大學社會精神保健教育研究中心，博士（日本）
2006.02-2008.02，西安交通大學臨床醫學，學士
2000.09-2003.07，西安醫學院，臨床醫學
1. Yao W#, Cao QQ#, Luo SL#, He LJ, Yang C, Chen JX, Qi Q*, Hashimoto K*, and Zhang JC* Microglial ERK-NRBP1-CREB-BDNF signaling in sustained antidepressant actions of (R)-ketamine, Molecular Psychiatry. 2021, in press. (IF: 15.992；JCR 1區；通訊作者)
2. Tang R#, Cao QQ#, Hu SW#, He LJ, Du PF, Chen G, Fu R, Xiao F, Sun YR*, Zhang JC* and Qi Q*. Sulforaphane activates anti-inflammatory microglia, modulating stress resilience associated with BDNF transcription, Acta Pharmacologica Sinica. 2021, in press. (IF: 6.150；JCR 1區；通訊作者)
3. Yao W#, Lin S#, Su J, Cao QQ, Chen YY, Chen JX, Zhang ZT, Hashimoto K*, Qi Q* and Zhang JC*. Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents, Transl Psychiatry. 2021, 11: 140. (IF: 6.222；JCR 1區；通訊作者)
4. Zhang JC, Yao W, Dong C, Han M, Shirayama Y, and Hashimoto K. Keap1–Nrf2 signaling pathway confers resilience versus susceptibility to inescapable electric stress. Eur Arch Psychiatry Clin Neurosci. 2018, 268 (8): 865-870. (IF: 3.569)
5. Zhang JC, Yao W, Qu YG, Nakamura M, Dong C, Yang C, Ren Q, Ma M, Han M, Shirayama Y, Hayashi-Takagi A, and Hashimoto K. Increased EphA4-ephexin1 signaling in the medial prefrontal cortex plays a role in depression-like phenotype. Sci Rep, 2017, 7: 7133. (IF: 4.259)
6. Zhang JC, Yao W, Dong C, Yang C, Ren Q, Ma M, Hashimoto K. Blockade of interleukin-6 receptor in the periphery promotes rapid and sustained antidepressant actions: a possible role of gut–microbiota–brain axis. Transl Psychiatry. 2017, 7, e1138. (IF: 5.182)
7. Zhang JC, Yao W, Dong C, Yang C Y, Ren Q, Ma M, Han M, Wu J, Ushida Y, Suganuma H, Hashimoto K. Prophylactic effects of sulforaphane on depression-like behavior and dendritic changes in mice after inflammation. J Nutr Biochem 2016, 39: 134–144. (IF: 4.490)
8. Zhang JC, Yao W, Ren Q, Yang C, Dong C, Ma M, Wu J & Hashimoto K. Depression-like phenotype by deletion of α7 nicotinic acetylcholine receptor: Role of BDNF-TrkB in nucleus accumbens. Sci Rep, 2016, 6: 36705. (IF: 4.259)
9. Zhang JC, Yao W, Hashimoto K. Brain-derived neurotrophic factor (BDNF) - TrkB signaling in inflammation-related depression and potential therapeutic targets. Current Neuropharmacology 2016, 14(7): 721-31. (IF: 4.068)
10. Zhang JC, Yao W, Dong C, Yang C, Ren Q, Ma M, Han M, Hashimoto K. Comparison of ketamine, 7,8-dihydroxyflavone and ANA-12 antidepressant effects in the social defeat stress model of depression. Psychopharmacology (Berl) 2015, 232(23): 4325-4335. (IF: 3.540)
11. Zhang JC, Wu J, Fujita Y, Yao W, Ren Q, Yang C, Li SX, Shirayama Y, Hashimoto K. Antidepressant effects of TrkB ligands on depression-like behavior and dendritic changes in mice after inflammation. Int J Neuropsychopharmacol 2015, 18(4): pyu077. (IF: 4.333)
1. 2021年度太阳集团1088vip“優秀科研工作者”
