利時雨

微生物與免疫學系 副教授

個人簡介


職稱:副教授(綠色通道聘)

學科專業:免疫學

研究方向:細胞外囊泡、老年醫學

行政職務:無

電子郵箱:lishuyu@jnu.edu.cn

個人介紹:利時雨,博士,太阳集团1088vip微生物與免疫學系副教授(綠色通道聘)。主要從事細胞外囊泡和線粒體靶點在老年醫學領域的治療應用,先後在Signal Transduction and Targeted Therapy、Advanced Science、Acta Biomaterialia等期刊發表SCI論文24篇。主持國自然青年基金、中國博士後科學基金、廣東省區域聯合基金青年項目、廣東省自然科學基金面上項目、太阳集团app首页科協青年科技人才托舉工程項目。參與國家重點研發計劃、國自然面上項目、廣東省區域聯合基金重點項目。


學習經曆


2018-09至2021-06,南方醫科大學,人體解剖與組織胚胎學專業,博士

2015-09至2018-06,南方醫科大學,生物化學與分子生物學專業,碩士

2009-09至2014-06,廣州醫科大學,臨床醫學專業,本科 


工作經曆


2024-06至今,太阳集团1088vip,副教授

2021-07至2024-05,南方醫科大學第三附屬醫院,博士後


主要論文


[1] Li S#, Liu S#, Jiang Z#, Feng L, Gao Y, Chen Y, Xu A, Huang W*, Zhang N*, Sun H*. Study on the promotion of lymphocytes in patients with COVID-19 by broad-spectrum chemokine receptor inhibitor vMIP-II and its Mechanism of signal transmission in vitro. Signal Transduct Target Ther. 2021 Mar 2;6(1):104. (IF38.1201Top

[2] Li S#, Zheng W#, Deng W#, Li Z, Yang J, Zhang H, Dai Z, Su W, Yan Z, Xue W, Yun X, Mi S, Shen J, Luo X, Wang L*, Wu Y*, Huang W*. Logic-Based Strategy for Spatiotemporal Release of Dual Extracellular Vesicles in Osteoarthritis Treatment. Adv Sci (Weinh). 2024 Jul;11(26):e2403227. (IF14.31Top

[3] Yang Y#, Zheng W#, Tan W#, Wu X#, Dai Z, Li Z, Yan Z, Ji Y, Wang Y, Su W, Zhong S, Li Y, Sun Y*, Li S*, Huang W*. Injectable MMP1-sensitive microspheres with spatiotemporally controlled exosome release promote neovascularized bone healing. Acta Biomater. 2023 Feb;157:321-336. (IF9.41Top

[4] Yan Z#, Yang J#, Zhang H#, Li Z, Zheng W, Li S*, Huang W*. The effect of depression status on osteoarthritis: A powerful two-step Mendelian randomization study. J Affect Disord. 2024 Nov 1;364:49-56. (IF4.9,二區Top

[5] Wang Y#, Li S#, Liu M, Wang J, Fei Z, Wang F, Jiang Z, Huang W*, Sun H*. Rhodosporidium toruloides sir2-like genes remodelled the mitochondrial network to improve the phenotypes of ageing cells. Free Radic Biol Med. 2019 Apr;134:64-75. (IF6.170,二區Top

[6] Zhang L#, Dai Z#, Shi S#, Yan Z, Yang J, Xue W, He Y, Mi S, Cheng C, Wang L, Li N, Tan W, Jiang Z*, Sun H*, Li S*. SIRT3 and SIRT4 double-genes remodeled the mitochondrial network to induce hepatocellular carcinoma cell line differentiation and suppress malignant phenotypes. Biochem Pharmacol. 2024 May;223:116168. (IF5.3,二區)

[7] Deng J#, Zhong Z#, Geng C#, Dai Z, Zheng W, Li Z, Yan Z, Yang J, Deng W, Tan W*, Sun H*, Li S*. Herpes Simplex Type 1 UL43 Multiple Membrane-Spanning Protein Increases Energy Metabolism in Host Cells through Interacting with ARL2. Cells. 2022 Nov 14;11(22):3594. (IF6.0,二區)

[8] Li Z#, Zhang H, Zheng W, Yan Z, Yang J, Li S*, Huang W*. Esaxerenone Protects against Diabetic Cardiomyopathy via Inhibition of the Chemokine and PI3K-Akt Signaling Pathway. Biomedicines. 2023 Dec 15;11(12):3319. (IF3.9,三區)

[9] Dai Z#, Li Z#, Zheng W#, Yan Z, Zhang L, Yang J, Xiao J, Sun H*, Li S*, Huang W*. Gallic Acid Ameliorates the Inflammatory State of Periodontal Ligament Stem Cells and Promotes Pro-Osteodifferentiation Capabilities of Inflammatory Stem Cell-Derived Exosomes. Life (Basel). 2022 Sep 6;12(9):1392. (IF3.2,三區)
[10] Li S#, Liu S#, Dai Z, Zhang Q, Xu Y, Chen Y, Jiang Z*, Huang W*, Sun H*. The UL16 protein of HSV-1 promotes the metabolism of cell mitochondria by binding to ANT2 protein. Sci Rep. 2021 Jul 7;11(1):14001. (IF4.997,三區)


獲獎及榮譽


第四屆廣東醫學科技獎-醫學科普獎 


學術兼職


廣東省生物醫學工程學會植入器械與先進制造分會委員

廣東省科普作家協會委員

廣東省精準醫學應用學會數字醫學分會會員

廣東省增材制造研究與應用協會會員

Regenerative Biomaterials、International Journal of Bioprinting、Cancer Cell International審稿人